Proquazone

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Proquazone
Proquazone.png
Systematic (IUPAC) name
1-isopropyl-7-methyl-4-phenylquinazolin-2(1H)-one
Identifiers
CAS Number 22760-18-5 N
ATC code M01AX13 (WHO)
PubChem CID 31508
ChemSpider 29222 N
UNII 42VPJ2980S N
ChEMBL CHEMBL268501 N
Chemical data
Formula C18H18N2O
Molar mass 278.34832 g/mol
 NYesY (what is this?)  (verify)

Proquazone is a non-steroidal anti-inflammatory drug.[1]

Synthesis[edit]

[2] [3]

References[edit]

  1. ^ Clissold, S. P.; Beresford, R. (1987). "Proquazone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases and pain states". Drugs. 33 (5): 478–502. doi:10.2165/00003495-198733050-00004. PMID 3297621. 
  2. ^ Coombs, R. V.; Danna, R. P.; Denzer, M.; Hardtmann, G. E.; Huegi, B.; Koletar, G.; Koletar, J.; Ott, H.; Jukniewicz, E. (1973). "Synthesis and antiinflammatory activity of 1-alkyl-4-aryl-2(1H)-quinazolines and quinazolinethiones". Journal of Medicinal Chemistry. 16 (11): 1237–1245. doi:10.1021/jm00269a006. ISSN 0022-2623. 
  3. ^ G. Gamboni, W. Schmid and A. Sutter; GB1592687 (1981 to Sandoz).