Prorenoic acid

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Prorenoic acid
Prorenoic acid.svg
Clinical data
SynonymsProrenoate; 6α,7α-Dihydro-17-hydroxy-3-oxo-3'H-cyclopropa(6,7)-17α-pregna-4,6-diene-21-carboxylic acid
Drug classAntimineralocorticoid
Identifiers
Chemical and physical data
FormulaC23H31O4
Molar mass371.497 g·mol−1
3D model (JSmol)

Prorenoic acid, or prorenoate, is a synthetic steroidal antimineralocorticoid which was never marketed.[1][2][3][4]

See also[edit]

References[edit]

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1036–. ISBN 978-1-4757-2085-3.
  2. ^ Claire M, Rafestin-Oblin ME, Michaud A, Roth-Meyer C, Corvol P (1979). "Mechanism of action of a new antialdosterone compound, prorenone". Endocrinology. 104 (4): 1194–200. doi:10.1210/endo-104-4-1194. PMID 436757.
  3. ^ Netchitailo P, Delarue C, Perroteau I, Jegou S, Tonon MC, Leroux P, Leboulenger F, Kusmierek MC, Capron MH, Vaudry H (1982). "Effect of aldosterone antagonists on mineralocorticoid synthesis in vitro. Inhibition of aldosterone production by prorenoate-K". Eur. J. Pharmacol. 77 (4): 243–9. PMID 6277668.
  4. ^ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 234–. ISBN 978-94-011-4439-1.