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Prosoplasia (from Ancient Greek: προσωπον prósopon , "face" + πλάσις plasis, "formation") is the differentiation of cells either to a higher function or to a higher level of organization.[1]

Assuming an increasing cellular peculiarity from a presuppossed stem-cell fate, prosoplasia is therefore a forward differentiation, unlike anaplasia (a backward differentiation). Examples of prosoplasia include the forward differentiation of cells in the mucosa in Warthin's tumor.[2]


  1. ^ Bignold, Leon P., Brian LD Coghlan, and Hubertus PA Jersmann. David Paul von Hansemann: contributions to oncology. Springer, 2007.
  2. ^ Rajendran, R. Shafer's textbook of oral pathology. Elsevier India, 2009.