Prostaglandin E

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PGE1 - Alprostadil
PGE2 - Dinoprostone

Prostaglandin E is a family of naturally occurring prostaglandins and may be used pharmaceutically in medicine.

Types include:

It is created from prostaglandin E synthase.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.[1]

Prostaglandin E2[edit]

Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.


  1. ^ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014. 

Pharmacology 2007. Rang, Dale, Ritter, Flower. Churchill Livingstone Elsevier.

External links[edit]