Pulmonary-renal syndrome

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Pulmonary-renal syndrome is a rare medical syndrome involving bleeding in the lungs and kidney damage[1] (glomerulonephritis).[2]


Causes are usually autoimmune.

It is most commonly due to granulomatosis with polyangiitis or Goodpasture's syndrome.

Other causes include systemic lupus erythematosus and microscopic polyangiitis.[3]


  1. ^ Herman, PG; Balikian JP; Seltzer SE; Ehrie M (June 1978). "The pulmonary-renal syndrome". American Journal of Roentgenology (American Roentgen Ray Society) 130 (6): 1141–1148. doi:10.2214/ajr.130.6.1141. PMID 418654. 
  2. ^ Sugimoto T, Deji N, Kume S et al. (2007). "Pulmonary-renal syndrome, diffuse pulmonary hemorrhage and glomerulonephritis, associated with Wegener's granulomatosis effectively treated with early plasma exchange therapy". Intern. Med. 46 (1): 49–53. doi:10.2169/internalmedicine.46.6070. PMID 17202734. 
  3. ^ "Pulmonary-Renal Syndrome: Diffuse Alveolar Hemorrhage and Pulmonary-Renal Syndrome: Merck Manual Professional". Retrieved 2010-04-09.