Pustulosis palmaris et plantaris (also known as pustulosis of palms and soles,palmoplantar pustulosis, persistent palmoplantar pustulosis, pustular psoriasis of the Barber type, and pustular psoriasis of the extremities) is a chronic recurrent pustular dermatosis (that is, a pustulosis or pustular psoriasis) localized on the palms and soles only, characterized histologically by intraepidermal pustules filled with neutrophils.:411,628:204 It can occur as part of the SAPHO syndrome.
Several treatments are used to improve the symptoms of palmoplantar pustulosis. Oral acitretin is found to be effective especially in combination with psoralens and ultraviolet radiation (PUVA) treatment. Other treatments include oral ciclosporin and tetracycline antibiotics.