"Putting Holes in Happiness" is Marilyn Manson's second single from his sixth studio albumEat Me, Drink Me. Written on his birthday (January 5, 2007), the song was initially set as the first single from the album, but this was soon changed at the request of Manson's record label, Interscope, and "Heart-Shaped Glasses (When the Heart Guides the Hand)" was released instead as the album's first single (similar to the case of "Get Your Gunn" from the band's debut). A two-track promotional disc was released in June 2007, but no confirmation of the song as the album's second single followed until Marilyn Manson confirmed the next single to be "Putting Holes in Happiness" on August 7, 2007. The song has already appeared on the radio in France, where a promo of the single has been sent out to several major radio stations.
On August 23, 2007, the music video for "Putting Holes in Happiness", created by the famous French filmmaker Philippe Grandrieux, was released on Yahoo!. Manson has stated in various interviews that select segments of the video were filmed in Germany during the shooting of the "Heart-Shaped Glasses (When the Heart Guides the Hand)" video in April 2007.