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Pyrazolo[3,4-b]pyridine, the base chemical structure of this class.

The pyrazolopyridines are a group of drugs investigated as anxiolytics which act as positive allosteric modulators of the GABAA receptor via the barbiturate binding site.[1][2] They include the following compounds:

See also[edit]


  1. ^ Annual Reports in Medicinal Chemistry: Volume 16. Amsterdam: Elsevier. 1981. ISBN 0-12-040516-4.
  2. ^ Progress in Drug Research / Volume 31 (Progress in Drug Research). Boston: Birkhauser. 1987. ISBN 3-7643-1837-6.