Pyrimidine analogue

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Pyrimidine analogues are nucleoside analog antimetabolites which mimic the structure of metabolic pyrimidines.


Medical Uses[edit]

Pyrimidine antimetabolites are commonly used to treat cancer by interfering with DNA replication.[1]


  1. ^ Parker, William B. (2009). "Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer". Chem Rev. 109 (7). doi:10.1021/cr900028p. Retrieved 2 March 2017.