Pyuria

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Not to be confused with Pyorrhea.
Pyuria
Pyuria.JPG
White blood cells seen under a microscope from a urine sample.
Classification and external resources
ICD-10 N39.0
ICD-9-CM 791.9
Patient UK Pyuria
MeSH D011776

In medicine, pyuria /pjʊəˈrə/ is the condition of urine containing white blood cells or pus. Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine. It can be a sign of a bacterial urinary tract infection. Pyuria may be present in the septic patient, or in an older patient with pneumonia.

Sterile pyuria[1] is urine which contains white blood cells while appearing sterile by standard culturing techniques. It is often caused by sexually transmitted infections, such as gonorrhea, or viruses which will not grow in bacterial cultures. Sterile pyuria is listed as a side effect from some medications such as paracetamol (acetaminophen). Its occurrence is also associated with certain disease processes, such as Kawasaki Disease and genitourinary tuberculosis.[2] However, there are many known causes, including systemic or infectious disease, structural and physiological reasons, intrinsic kidney pathology, or drugs.[2]

Pyuria in a person with urosepsis

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References[edit]

  1. ^ Gilbert J. Wise and Peter N. Schlegel (March 12, 2015). "Sterile Pyuria". N Engl J Med 372 (11): 1048–1054. doi:10.1056/NEJMra1410052. 
  2. ^ a b Dieter RS (2000). "Sterile pyuria: a differential diagnosis". Compr Ther 26 (3): 150–2. doi:10.1007/s12019-000-0001-1. PMID 10984817. 

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