From Wikipedia, the free encyclopedia
Jump to: navigation, search
IUPAC name
Other names
(3aS,6aR,7aS,8S,11aS,11bS,11cS) -1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a,11c- tetramethyldibenzo[de,g]chromene-1,5,11-trione
3D model (Jmol)
ECHA InfoCard 100.000.897
EC Number 200-985-9
Molar mass 388.46 g·mol−1
Appearance White crystalline substance
Melting point 200 to 222 °C (392 to 432 °F; 473 to 495 K)
Boiling point 586 °C (1,087 °F; 859 K)
Vapor pressure 13 mmHg (@25 °C)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Quassin is a white bitter, crystalline substance that is the prototypical example of the family of quassinoids. It can be extracted from the quassia tree, from which it gets its name. It was first isolated in 1937 and its chemical structure was elucidated in 1961. It is one of the most bitter substances found in nature, with a bitter threshold of 0.08 ppm and it is 50 times more bitter than quinine.[1]

Extracts of the bitterwood tree (Quassia amara) containing quassin are used as additives in soft drinks.[1]

Although its skeleton possesses 20 carbon atoms, quassin is not a diterpene but rather a triterpene lactone, which derives from euphol by loss of 10 carbon atoms including C4.


  1. ^ a b Scientific Committee on Food Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002). SCF/CS/FLAV/FLAVOUR/29 Final