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Skeletal formula of quinuclidine
Ball-and-stick model of quinuclidine
IUPAC name
100-76-5 YesY
ChEBI CHEBI:38420 YesY
ChEMBL ChEMBL1209648 YesY
ChemSpider 7246 YesY
Jmol interactive 3D Image
PubChem 7527
Molar mass 111.18 g/mol
Density 0.97g/cm3
Melting point 157 to 160 °C (315 to 320 °F; 430 to 433 K)
Boiling point 149.5 °C (301.1 °F; 422.6 K) at 760 mmHg
Acidity (pKa) 12.1 (conjugate acid)
Flash point 36.5 °C (97.7 °F; 309.6 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 11.0.[2] This is due to greater availability of the nitrogen lone pair[citation needed]. It can be prepared by reduction of quinuclidone.

The compound is structurally related to DABCO in which the other bridgehead is also nitrogen and tropane with a slightly different carbon frame.

Quinuclidine is found as a structural component of some biomolecules including quinine.


  1. ^ Quinuclidine at Sigma-Aldrich
  2. ^ Hext, N. M.; Hansen, J.; Blake, A. J.; Hibbs, D. E.; Hursthouse, M. B.; Shishkin, O. V.; Mascal, M. (1998). "Azatriquinanes: Synthesis, Structure, and Reactivity". J. Org. Chem. 63 (17): 6016–6020. doi:10.1021/jo980788s. PMID 11672206.