R15, R-15, or similar, may refer to:
- R-15 (novel series), a 2009 Japanese novel series by Hiroyuki Fushimi and Takuya Fujima
- R-15 (missile), a Soviet submarine-launched ballistic missile design
- R15 (New York City Subway car), a subway car built in 1950
- R15: Contact with water liberates extremely flammable gases, a risk phrase
- Tumansky R-15, an axial flow, single shaft turbojet with afterburning capabilities
- USS R-15 (SS-92), a 1918 R-class coastal and harbor defense submarine of the United States Navy
- AR-15, a lightweight, air-cooled, magazine fed, autoloading, centerfire shoulder-fired rifle
- Renault 15, a car
- R15 (Rodalies de Catalunya), a regional rail line in Catalonia, Spain
- Yamaha R15, a motorcycle sold in India and Colombia
- Audi R15, a Le Mans prototype racing car
- HMS Colossus (R15), see French aircraft carrier Arromanches (R95)
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