R-410A, sold under the trademarked names AZ-20, EcoFluor R410, Forane 410A, Freon 410A, Genetron R410A, Puron, and Suva 410A is a zeotropic, but near-azeotropic mixture of difluoromethane (CH2F2, called R-32) and pentafluoroethane (CHF2CF3, called R-125), which is used as a refrigerant in air conditioning applications. R-410A cylinders are colored pink.
R-410A was invented and patented by Allied Signal (now Honeywell) in 1991.  Other producers around the world have been licensed to manufacture and sell R-410A, but Honeywell continues to be the leader in capacity and sales. R-410A was successfully commercialized in the air conditioning segment by a combined effort of Carrier Corporation, Emerson Climate Technologies, Inc., Copeland Scroll Compressors (a division of Emerson Electric Company), and Allied Signal. Carrier Corporation was the first company to introduce an R-410A based residential air conditioning unit onto the marketplace in 1996 and holds the trademark "Puron".
R-410A has replaced R-22 as the preferred refrigerant for use in residential and commercial air conditioners in Japan, Europe and the United States. 
Parts designed specifically for R-410A must be used as R-410A operates at higher pressures than other refrigerants. R-410A systems thus require service personnel to use different tools, equipment, safety standards, and techniques. Equipment manufacturers are aware of these changes and require the certification of professionals installing R-410A systems. In addition, the AC&R Safety Coalition has been created to help educate professionals about R-410A systems.
In accordance with terms and agreement reached in the Montreal Protocol (The Montreal Protocol on Substances that Deplete the Ozone Layer) the United States Environmental Protection Agency has mandated that production or import of R-22 along with other hydrochlorofluorocarbons (HCFCs) be phased out in the United States. In the EU and the US, virgin R-22 cannot be used in the manufacture of new air conditioning or similar units from 1 January 2010. In other parts of the world the phase-out date varies from country to country. Today, all newly manufactured window unit air conditioners and mini split air conditioners in the United States come with R-410A. From the beginning of 2020, the production and importation of R-22 will be banned, after which the only available sources of R-22 will be that which has been stockpiled or recovered from existing devices.
|Molecular Weight (Da)||72.6|
|Melting point (°C)||−155|
|Boiling point (°C)||−48.5|
|Liquid density (30°C), kg/m3||1040|
|Vapour density (30°C), air=1.0||3.0|
|Vapour pressure at 21.1°C (MPa)||1.383|
|Critical temperature (°C)||72.8|
|Critical pressure, MPa||4.86|
|Gas heat capacity (kJ/(kg·°C))||0.84|
|Liquid heat capacity @ 1 atm, 30°C, (kJ/(kg·°C))||1.8|
Thermophysical properties - http://twt.mpei.ac.ru/TTHB/2/R410a-eng.html
Unlike alkyl halide refrigerants that contain bromine or chlorine, R-410A (which contains only fluorine) does not contribute to ozone depletion, and is therefore becoming more widely used, as ozone-depleting refrigerants like R-22 are phased out. However, it has a high global warming potential (1700 times the effect of carbon dioxide), similar to that of R-22.  Since R-410A allows for higher SEER ratings than an R-22 system, by reducing power consumption, the overall impact on global warming of R-410A systems will be substantially lower than that of R-22 systems due to reduced greenhouse gas emissions from power plants.
- AZ-20 Story - About R-410A - R-410A - Honeywell AZ-20 Refrigerant Archived 2007-11-16 at the Wayback Machine.
- Certification - R-410A - Honeywell AZ-20 Refrigerant Archived 2007-11-25 at the Wayback Machine.
- "PURON - Reviews & Brand Information - Carrier Corporation SYRACUSE, NY - Serial Number: 77215886". Trademarkia.com. Retrieved 2016-05-01.
- "Site Maintenance". Commercial.carrier.com. Retrieved 2016-05-01.
- EPA R-22 Phase-out
- "R-410A Certification FAQ". Mainstream Engineering Corporation. Retrieved 2009-03-05.
- Honeywell AZ-20 (R-410A) Refrigerant
- "R-410a Material Safety Data Sheet" (PDF). Honeywell International Inc. Archived from the original (PDF) on 2010-10-11. Retrieved 2009-07-03.
- "Puron Refrigerant R-410A" (PDF). Archived from the original on 21 December 2006. Retrieved 2 July 2014.
- "R-410A" (PDF). Honeywell Refrigerants Europe. Archived from the original (PDF) on 27 March 2014. Retrieved 26 April 2013.
- IPCC Assessment Report 4 (AR4) 2007
- "The Essentials Of Working With R-410A" (PDF). Florida State College at Jacksonville. p. 7. Archived from the original (PDF) on September 4, 2014. Retrieved November 21, 2013.