RAB6A

From Wikipedia, the free encyclopedia
Jump to: navigation, search
RAB6A
Protein RAB6A PDB 1yzq.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases RAB6A, RAB6, member RAS oncogene family
External IDs MGI: 894313 HomoloGene: 55697 GeneCards: RAB6A
RNA expression pattern
PBB GE RAB6A 201045 s at fs.png

PBB GE RAB6A 201047 x at fs.png

PBB GE RAB6A 210406 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198896
NM_001243718
NM_001243719
NM_002869

NM_001163663
NM_024287

RefSeq (protein)

NP_001230647
NP_001230648
NP_002860
NP_942599

NP_001157135.1
NP_077249.1
NP_001157135
NP_077249

Location (UCSC) Chr 11: 73.68 – 73.76 Mb Chr 7: 100.61 – 100.64 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome.[3] Its main function is the regulation of protein transport from the Golgi complex to the endoplasmic reticulum and the exocytosis along with the microtubules.

Interactions[edit]

RAB6A has been shown to interact with:

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: RAB6A RAB6A, member RAS oncogene family". 
  4. ^ a b Short B, Preisinger C, Schaletzky J, Kopajtich R, Barr FA (October 2002). "The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes". Curr. Biol. 12 (20): 1792–5. doi:10.1016/s0960-9822(02)01221-6. PMID 12401177. 
  5. ^ Matanis T, Akhmanova A, Wulf P, Del Nery E, Weide T, Stepanova T, Galjart N, Grosveld F, Goud B, De Zeeuw CI, Barnekow A, Hoogenraad CC (December 2002). "Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex". Nat. Cell Biol. 4 (12): 986–92. doi:10.1038/ncb891. PMID 12447383. 
  6. ^ Monier S, Jollivet F, Janoueix-Lerosey I, Johannes L, Goud B (April 2002). "Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport". Traffic. 3 (4): 289–97. doi:10.1034/j.1600-0854.2002.030406.x. PMID 11929610. 
  7. ^ Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. doi:10.1126/science.279.5350.580. PMID 9438855. 
  8. ^ Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039Freely accessible. PMID 11071909. 

Further reading[edit]