RABEPK

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RABEPK
Identifiers
Aliases RABEPK, RAB9P40, bA65N13.1, p40, Rab9 effector protein with kelch motifs
External IDs MGI: 2139530 HomoloGene: 48772 GeneCards: RABEPK
RNA expression pattern
PBB GE RABEPK 203150 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001174152
NM_001174153
NM_005833

NM_145522

RefSeq (protein)

NP_001167623
NP_001167624
NP_005824

NP_663497.2
NP_663497

Location (UCSC) Chr 9: 125.2 – 125.23 Mb Chr 2: 34.78 – 34.8 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.[3][4]

Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.[3]

Interactions[edit]

RABEPK has been shown to interact with RAB9A[3] and FYVE finger-containing phosphoinositide kinase.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b c Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol. 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197Freely accessible. PMID 9230071. 
  4. ^ "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs". 
  5. ^ Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. United States. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284. 

Further reading[edit]

External links[edit]