RAP2B

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RAP2B
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases RAP2B, member of RAS oncogene family
External IDs MGI: 1921262 HomoloGene: 55701 GeneCards: RAP2B
RNA expression pattern
PBB GE RAP2B 214488 at fs.png

PBB GE RAP2B 213923 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002886

NM_028712

RefSeq (protein)

NP_002877

NP_082988.1
NP_082988

Location (UCSC) Chr 3: 153.16 – 153.17 Mb Chr 3: 61.36 – 61.37 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rap-2b is a protein that in humans is encoded by the RAP2B gene.[3][4] RAP2B belongs to the Ras-related protein family.

This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ohmstede CA, Farrell FX, Reep BR, Clemetson KJ, Lapetina EG (Oct 1990). "RAP2B: a RAS-related GTP-binding protein from platelets". Proc Natl Acad Sci U S A. 87 (17): 6527–31. doi:10.1073/pnas.87.17.6527. PMC 54569Freely accessible. PMID 2118648. 
  4. ^ a b "Entrez Gene: RAP2B RAP2B, member of RAS oncogene family". 

Further reading[edit]