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Protein RELB PDB 1zk9.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases RELB, I-REL, IREL, REL-B, RELB proto-oncogene, NF-kB subunit, IMD53
External IDs MGI: 103289 HomoloGene: 4747 GeneCards: RELB
Gene location (Human)
Chromosome 19 (human)
Chr. Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for RELB
Genomic location for RELB
Band 19q13.32 Start 45,001,430 bp[1]
End 45,038,198 bp[1]
RNA expression pattern
PBB GE RELB 205205 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 19: 45 – 45.04 Mb Chr 19: 19.61 – 19.63 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Transcription factor RelB is a protein that in humans is encoded by the RELB gene.[5]


RELB has been shown to interact with NFKB2,[6][7] NFKB1,[6] and C22orf25.[8]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000104856 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002983 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck RP, Bravo R, Kelly K, Siebenlist U (Feb 1992). "A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site". Molecular and Cellular Biology. 12 (2): 685–95. PMC 364259Freely accessible. PMID 1531086. 
  6. ^ a b Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G (Feb 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. 
  7. ^ Thornburg NJ, Pathmanathan R, Raab-Traub N (Dec 2003). "Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma". Cancer Research. 63 (23): 8293–301. PMID 14678988. 
  8. ^ "Molecular Interaction Database". 

Further reading[edit]