RENBP

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RENBP
Identifiers
Aliases RENBP, RBP, RNBP, renin binding protein
External IDs MGI: 105940 HomoloGene: 2184 GeneCards: RENBP
RNA expression pattern
PBB GE RENBP 206617 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002910

NM_001164704
NM_023132

RefSeq (protein)

NP_002901

NP_001158176.1
NP_075621.3
NP_001158176
NP_075621

Location (UCSC) Chr X: 153.94 – 153.94 Mb Chr X: 73.92 – 73.93 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

N-acylglucosamine 2-epimerase is an enzyme that in humans is encoded by the RENBP gene.[3][4]

The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Takahashi S, Inoue H, Miyake Y (Aug 1992). "The human gene for renin-binding protein". J Biol Chem. 267 (18): 13007–13. PMID 1618798. 
  4. ^ a b "Entrez Gene: RENBP renin binding protein". 

Further reading[edit]