RFX3

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RFX3
Identifiers
Aliases RFX3
External IDs MGI: 106582 HomoloGene: 7917 GeneCards: 5991
RNA expression pattern
PBB GE RFX3 207234 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001282116
NM_001282117
NM_002919
NM_134428

NM_001166414
NM_011265

RefSeq (protein)

NP_001269045.1
NP_001269046.1
NP_002910.1
NP_602304.1

NP_001159886.1
NP_035395.2

Location (UCSC) Chr 9: 3.22 – 3.53 Mb Chr 19: 27.76 – 28.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.[3][4]

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.[4]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.