RGS11

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RGS11
Identifiers
Aliases RGS11, RS11, regulator of G-protein signaling 11, regulator of G protein signaling 11
External IDs MGI: 1354739 HomoloGene: 77719 GeneCards: RGS11
Gene location (Human)
Chromosome 16 (human)
Chr. Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for RGS11
Genomic location for RGS11
Band 16p13.3 Start 268,301 bp[1]
End 275,980 bp[1]
RNA expression pattern
PBB GE RGS11 211872 s at fs.png

PBB GE RGS11 206107 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286485
NM_001286486
NM_003834
NM_183337

NM_001081069

RefSeq (protein)

NP_001273414
NP_001273415
NP_003825
NP_899180

NP_001074538

Location (UCSC) Chr 16: 0.27 – 0.28 Mb Chr 17: 26.2 – 26.21 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Regulator of G-protein signaling 11 is a protein that in humans is encoded by the RGS11 gene.[5][6]

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.[6]

References[edit]

Further reading[edit]