RH-34

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RH-34
RH-34 structure.png
Systematic (IUPAC) name
3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione
Clinical data
Routes of
administration
?
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number 1028307-48-3 N
ATC code none
PubChem CID 10041987
ChemSpider 8217551
UNII A31AED225O YesY
Chemical data
Formula C18H19N3O3
Molar mass 325.361 g/mol
 NYesY (what is this?)  (verify)

RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.[1][2][3]

Legal status[edit]

RH-34 is a controlled substance in Hungary.[4]

See also[edit]

References[edit]