RNA polymerase II subunit B4

POLR2D
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2C35, 5IYD, 5IY8, 5IYC, 5IY6, 5IY7, 5IYA, 5IY9, 5IYB
Identifiers
Aliases	POLR2D, HSRBP4, HSRPB4, RBP4, RPB16, RNA polymerase II subunit B4, polymerase (RNA) II subunit D, RNA polymerase II subunit D, RPB4
External IDs	OMIM: 606017; MGI: 1916491; HomoloGene: 37968; GeneCards: POLR2D; OMA:POLR2D - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q14.3 Start 127,843,553 bp End 127,858,155 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 B1 Start 31,922,212 bp End 31,929,754 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell left testis right testis pancreatic ductal cell tibialis anterior muscle ganglionic eminence ventricular zone islet of Langerhans gastrocnemius muscle quadriceps femoris muscle Top expressed in primary oocyte yolk sac ventricular zone embryo embryo secondary oocyte epiblast endocardial cushion medial ganglionic eminence morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding DNA-directed 5'-3' RNA polymerase activity single-stranded DNA binding catalytic activity single-stranded RNA binding translation initiation factor binding Cellular component P-body RNA polymerase II, core complex nucleus nucleoplasm cytosol nuclear speck nuclear DNA-directed RNA polymerase complex RNA polymerase complex Biological process mRNA splicing, via spliceosome recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex transcription elongation from RNA polymerase II promoter 7-methylguanosine mRNA capping transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cell metabolism transcription-coupled nucleotide-excision repair transcription initiation from RNA polymerase II promoter positive regulation of translational initiation mRNA export from nucleus in response to heat stress fibroblast growth factor receptor signaling pathway snRNA transcription by RNA polymerase II RNA metabolic process regulation of gene silencing by miRNA DNA-templated transcription, initiation transcription, DNA-templated somatic stem cell population maintenance positive regulation of viral transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5433 69241 Ensembl ENSG00000144231 ENSMUSG00000024258 UniProt O15514 Q9D7M8 RefSeq (mRNA) NM_004805 NM_027002 NM_001357480 RefSeq (protein) NP_004796 NP_081278 NP_001344409 Location (UCSC) Chr 2: 127.84 – 127.86 Mb Chr 18: 31.92 – 31.93 Mb PubMed search
Wikidata
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DNA-directed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene.