RNase D

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Ribonuclease D
Crystal structure 1YT3.jpg
Structure of the RNase D protein
Other data
EC number

RNase D is one of the seven exoribonucleases identified in E. coli. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing of various stable RNA molecules.[1] It is known to add the 3' CCA sequence to tRNA in prokaryotic tRNA processing. RNase D has homologues in many other organisms. When a part of another larger protein has a domain that is very similar to RNase D, this is called an RNase D domain.


  1. ^ Zuo; Wang, Y; Malhotra, A; et al. (2005). "Crystal structure of Escherichia coli RNase D, an exoribonuclease involved in structured RNA processing". Structure. 13 (7): 973–84. doi:10.1016/j.str.2005.04.015. PMID 16004870. 

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