RNase R

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RNase R is an 3'-->5' exoribonuclease closely related to RNase II, which has been shown to be involved in selective mRNA degradation, particularly of non stop mRNAs in bacteria.[1][2] RNase R has homologues in many other organisms. When a part of another larger protein has a domain that is very similar to RNase R, this is called an RNase R domain.


  1. ^ Cheng; Deutscher, MP; et al. (2005). "An important role for RNase R in mRNA decay". Molecular Cell. 17 (2): 313–8. doi:10.1016/j.molcel.2004.11.048. PMID 15664199. 
  2. ^ Venkataraman, K; Guja, KE; Garcia-Diaz, M; Karzai, AW (2014). "Non-stop mRNA decay: a special attribute of trans-translation mediated ribosome rescue.". Frontiers in Microbiology. 5: 93. doi:10.3389/fmicb.2014.00093. PMC 3949413Freely accessible. PMID 24653719.