40S ribosomal protein S25

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Available structures
PDB Ortholog search: PDBe RCSB
Aliases RPS25, S25, ribosomal protein S25
External IDs MGI: 1922867 HomoloGene: 133893 GeneCards: RPS25
Gene location (Human)
Chromosome 11 (human)
Chr. Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for RPS25
Genomic location for RPS25
Band 11q23.3 Start 119,015,712 bp[1]
End 119,018,691 bp[1]
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 11: 119.02 – 119.02 Mb Chr 11: 44.41 – 44.41 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

40S ribosomal protein S25 is a protein that in humans is encoded by the RPS25 gene.[5][6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]


RPS25 has been shown to interact with CDC5L.[7]


  1. ^ a b c ENSG00000118181 GRCh38: Ensembl release 89: ENSG00000280831, ENSG00000118181 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000009927 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Li ML, Latoud C, Center MS (January 1992). "Cloning and sequencing a cDNA encoding human ribosomal protein S25". Gene. 107 (2): 329–33. doi:10.1016/0378-1119(91)90335-9. PMID 1748303. 
  6. ^ a b "Entrez Gene: RPS25 ribosomal protein S25". 
  7. ^ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. ENGLAND. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846Freely accessible. PMID 11101529. 

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