From Wikipedia, the free encyclopedia
Jump to: navigation, search
RRN3 homolog, RNA polymerase I transcription factor
Symbols RRN3 ; A-270G1.2; TIFIA
External IDs OMIM605121 MGI1925255 HomoloGene39531 GeneCards: RRN3 Gene
RNA expression pattern
PBB GE RRN3 216902 s at tn.png
PBB GE RRN3 216908 x at tn.png
PBB GE RRN3 222204 s at tn.png
More reference expression data
Species Human Mouse
Entrez 54700 106298
Ensembl ENSG00000085721 ENSMUSG00000022682
UniProt Q9NYV6 B2RS91
RefSeq (mRNA) NM_001301064 NM_001039521
RefSeq (protein) NP_001287993 NP_001034610
Location (UCSC) Chr 16:
15.06 – 15.09 Mb
Chr 16:
13.78 – 13.81 Mb
PubMed search [1] [2]

RNA polymerase I-specific transcription initiation factor RRN3 is an enzyme that in humans is encoded by the RRN3 gene.[1][2][3]


RRN3 has been shown to interact with TAF1B.[2]


  1. ^ Moorefield B, Greene EA, Reeder RH (May 2000). "RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human". Proc. Natl. Acad. Sci. U.S.A. 97 (9): 4724–9. doi:10.1073/pnas.080063997. PMC 18300. PMID 10758157. 
  2. ^ a b Miller G, Panov KI, Friedrich JK, Trinkle-Mulcahy L, Lamond AI, Zomerdijk JC (Mar 2001). "hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters". EMBO J. 20 (6): 1373–82. doi:10.1093/emboj/20.6.1373. PMC 145519. PMID 11250903. 
  3. ^ "Entrez Gene: RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)". 

Further reading[edit]