RTI-171

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RTI-171
RTI-171 structure.png
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
Formula C19H24N2O
Molar mass 296.406 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

(–)-2β-(3-Methylisoxazol-5-yl)-3β-(p-tolyl)tropane (RTI-4229-171) is a phenyltropane derivative which acts as a selective dopamine reuptake inhibitor, with a relatively slow onset of action and short duration of effects found in animal studies.[1] However, other studies have shown it to have the most pronounced effects in terms of speed of onset and rate of stimulation among many differing phenyltropanes.[2]

See also[edit]

References[edit]

  1. ^ Kimmel HL, Carroll FI, Kuhar MJ (December 2001). "Locomotor stimulant effects of novel phenyltropanes in the mouse". Drug and Alcohol Dependence. 65 (1): 25–36. PMID 11714587. doi:10.1016/S0376-8716(01)00144-2. 
  2. ^ Kimmel, Heather L.; O'Connor, Joann A.; Carroll, F. Ivy; Howell, Leonard L. (2007). "Faster onset and dopamine transporter selectivity predict stimulant and reinforcing effects of cocaine analogs in squirrel monkeys". Pharmacology Biochemistry and Behavior. 86 (1): 45–54. ISSN 0091-3057. PMC 1850383Freely accessible. PMID 17258302. doi:10.1016/j.pbb.2006.12.006.