|Chemical and physical data|
|Molar mass||228.289 g/mol|
|3D model (JSmol)|
|NY (what is this?)|
RU-24,969 is a drug and research chemical widely used in scientific studies. It is a selective agonist at the 5-HT1A and 5-HT1B receptors, with preference for the latter. As with other 5-HT1B agonists such as CP-94,253, RU-24,969 has been found to increase the reinforcing properties of cocaine, suggesting a role for 5-HT1B receptors in cocaine addiction.
- Doods HN, Kalkman HO, De Jonge A, Thoolen MJ, Wilffert B, Timmermans PB, Van Zwieten PA (1985). "Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity". Eur J Pharmacol. 112 (3): 363–370. doi:10.1016/0014-2999(85)90782-4. PMID 3160596.
- Parsons LH, Weiss F, Koob GF (December 1998). "Serotonin1B receptor stimulation enhances cocaine reinforcement". Journal of Neuroscience. 18 (23): 10078–89. PMID 9822762.
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