RYR3

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RYR3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRYR3, RYR-3, ryanodine receptor 3
External IDsMGI: 99684 HomoloGene: 68151 GeneCards: RYR3
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for RYR3
Genomic location for RYR3
Band15q13.3-q14Start33,310,945 bp[1]
End33,866,121 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001036
NM_001243996

NM_177652
NM_001319156

RefSeq (protein)

NP_001027
NP_001230925

NP_001306085
NP_808320

Location (UCSC)Chr 15: 33.31 – 33.87 MbChr 2: 112.63 – 113.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ryanodine receptor 3 is a protein that in humans is encoded by the RYR3 gene.[5] The protein encoded by this gene is both a calcium channel and a receptor for the plant alkaloid ryanodine. RYR3 and RYR1 control the resting calcium ion concentration in skeletal muscle.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198838 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057378 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Sorrentino V, Giannini G, Malzac P, Mattei MG (Feb 1994). "Localization of a novel ryanodine receptor gene (RYR3) to human chromosome 15q14-q15 by in situ hybridization". Genomics. 18 (1): 163–5. doi:10.1006/geno.1993.1446. PMID 8276408. 
  6. ^ Perez CF, López JR, Allen PD (March 2005). "Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle". Am. J. Physiol., Cell Physiol. 288 (3): C640–9. doi:10.1152/ajpcell.00407.2004. PMID 15548569. 

Further reading[edit]

External links[edit]