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Born in Cairo, Egypt, his family moved to the United States when Naam was three years old. 
Naam was involved in the development of software products such as Microsoft Internet Explorer and Microsoft Outlook. He was the CEO of Apex Nanotechnologies, a company involved in developing nanotechnology research software, before returning to Microsoft.[unreliable source?] His last role at Microsoft was as a Partner Group Program Manager in Search Relevance for Live Search. Naam currently holds a seat on the advisory board of the Acceleration Studies Foundation, is a member of the World Future Society, a Senior Associate of the Foresight Institute, and a fellow of the Institute for Ethics and Emerging Technologies.[unreliable source?][unreliable source?]
- More than Human: Embracing the Promise of Biological Enhancement. Broadway Books, 2005
- The Infinite Resource: The Power of Ideas on a Finite Planet. University Press of New England, 2013
The Nexus Trilogy
2015 Apex won the Philip K. Dick Award.