|Date of birth||21 January 1983|
|Place of birth||Loznica, SFR Yugoslavia|
|Height||1.86 m (6 ft 1 in)|
|2004–2005||→ Mačva Šabac (loan)||32||(1)|
|2009–2010||→ Salamanca (loan)||24||(4)|
|2011–2013||Urawa Red Diamonds||25||(1)|
|* Senior club appearances and goals counted for the domestic league only and correct as of 19 March 2017.
Born in Loznica, Serbia, Socialist Federal Republic of Yugoslavia, Despotović made his professional debuts with local FK Loznica aged only 17, and proceeded to score almost 30 goals overall in his first three years, subsequently being acquired by FK Vojvodina.
After parts of seasons loaned to lowly FK Mačva Šabac, he returned, having a stellar 2006–07 season and helping the team to the third place in the league and coming up second in the domestic cup; to help achieve this, he topped the nation's goal charts by netting 17 times.
In January 2008, Despotović signed with FC Rapid București in Romania, and continued abroad for the ensuing summer as he joined Spain's Real Murcia for three years and €1.5 million. He was brought to the club by head coach Javier Clemente, who became aware of the player while coaching the national team of Serbia.
For the 2009–10 campaign, Despotović stayed in the country and its second division, moving on a season-long loan to UD Salamanca. The following year, still in that level, he led Girona FC with 18 goals (seventh-best in the competition) as the Catalans finished comfortably in mid-table.
On 1 July 2011, Despotović signed for Japan's Urawa Red Diamonds. In late 2013, following an unsuccessful trial at former club Girona, he moved to Sydney FC, after being convinced to join by former Vojvodina teammate Nikola Petković. He made his debut for his new team against Wellington Phoenix FC, coming on as a substitute and scoring the 2–1 winner in injury time.
|Mačva Šabac (loan)||2003–04||15||4||–||0||0||15||4|
|Urawa Red Diamonds||2011||14||0||1||0||5||4||–||20||4|
2Includes J. League Cup.
3Includes UEFA Cup qualification.
- "Despotović predstavljen u Mursiji" [Despotović signs for Murcia] (in Serbian). B92. 4 July 2008.
- "Despotovic y David Cuéllar se marchan al Salamanca" [Despotovic and David Cuéllar move to Salamanca]. Marca (in Spanish). 31 August 2009. Retrieved 17 February 2014.
- "Charles escala en el podio de los goleadores extranjeros" [Charles reaches podium of foreign top scorers]. El Día de Córdoba (in Spanish). 16 May 2011. Retrieved 17 February 2014.
- "Despotovic: traspàs històric" [Despotovic: historic transfer] (in Catalan). Girona FC. 29 June 2011. Retrieved 2 July 2011.
- ランコ デスポトビッチ選手、加入決定 (in Japanese). Urawa Red Diamonds. 2 July 2011. Retrieved 2 July 2011.
- "Despotovic, a un paso de volver al Girona" [Despotovic, on the verge of returning to Girona]. Mundo Deportivo (in Spanish). 13 July 2013. Retrieved 17 February 2014.
- "Sydney FC debutant Ranko Despotovic scores last-minute winner to beat Wellington 2–1". Fox Sports. 23 November 2013. Retrieved 2 May 2016.
- "El Alavés incorpora a sus filas al delantero serbio Ranko Despotovic" [Alavés add Serbian striker Ranko Despotovic to ranks] (in Spanish). Deportivo Alavés. 7 July 2014. Retrieved 10 July 2014.
- Despotovic, Chaco, Alex Serrano y Graxa, primeras bajas en el Marbella FC (Despotovic, Chaco, Alex Serrano and Graxa, first out at Marbella FC); Estepona Press, 28 December 2016 (in Spanish)
- "Clemente names 10 debutants for Serbia's final qualifier". Reuters. 22 November 2007. Archived from the original on 19 December 2007. Retrieved 22 November 2007.
- "R. Despotović". Soccerway.
- "Ranko Despotović". Worldfootball.