Raphael Carl Lee

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Raphael Carl Lee (born October 29, 1949 Sumter, South Carolina) is an American surgeon, medical researcher, biomedical engineer, and entrepreneur.


Lee spent his childhood and adolescence in South Carolina. During medical school and graduate school he lived in Philadelphia, Chicago and Boston. Today, he practices reconstructive plastic surgery at the University of Chicago. Mostly his research has focused on advancing the care of trauma victims. Lee is recognized for the application of multiblock copolymer surfactants to mimic behavior of natural chaperone proteins to augment the body's self-repair capability following major injury. He has also contributed to understanding the biophysical mechanisms of tissue injury in victims of electrical shock.

He serves as the Paul S. and Ailene T. Russell Professor of Surgery at the University of Chicago, and holds appointments in the departments of Medicine (Dermatology), Molecular Medicine, and Organismal Biology & Anatomy. Dr. Lee is the Director of the University of Chicago's Laboratory for Molecular Regeneration.

He graduated from the University of South Carolina, in electrical engineering in 1971, and Temple University School of Medicine and Drexel University with M.D. and M.S. degrees in 1975.[1] He was a resident in surgery at the University of Chicago Hospitals in 1975 to 1981 and at the Massachusetts General Hospital 1981 to 1983. While a resident at the University of Chicago, he enrolled in the Harvard-MIT Division of Health Sciences and Technology doctoral program. He received a Sc.D. in bioelectrical engineering from the Massachusetts Institute of Technology in 1979.[2]

He a clinical investigator at the University of Chicago.[3]

He is Founder and Chairman of RenaCyte BioMolecular Technologies (2005) and Avocet Polymer Technologies,Inc (1997). He is affiliated with the Chicago Electrical Trauma Research Institute.

Selected Awards[edit]


  • Raphael C Lee, Mary Capelli-Schellpfeffer, and Kathleen M. Kelley, eds. (1994). Electrical Injury: A Multidisciplinary Approach to Prevention, Therapy & Rehabilitation. New York Academy of Sciences. ISBN 0-89766-864-2. 
  • Chin-tu Chen, Raphael C Lee, J-X Shih, and Min-Ha Zhong, eds. (1999). Occupational Electrical Injury and Safety. New York Academy of Sciences. ISBN 1-57331-232-0. 
  • Raphael C Lee, Florin Despa, Kimm Jon Hamann,, eds. (2005). Cell injury: mechanisms, responses, and repair. New York Academy of Sciences. ISBN 978-1-57331-616-3. 
  • Raphael C Lee and Anna Chien The Doctor's Plague: Germs, Childbed Fever, and the Strange Story of Ignac Semmelweis. (Book Review) Perspectives in Biology and Medicine - Volume 48, Number 4, Autumn 2005, pp. 616–618
  • M. Capelli-Schellpfeffer, M. and R.C.Lee, "Electrical Shock” in Encyclopedia of Electrical and Electronics Engineering, Webster, J.G., Ed., John Wiley and Sons, New York, 1998

Author or coauthor of more than 200 journal publications and book chapters


  1. ^ "Department of Surgery - Faculty - Raphael Lee, MD". University of Chicago. Retrieved 2010-05-31. 
  2. ^ "The HistoryMakers Video Oral History Interview with Raphael Lee". The HistoryMakers. May 23, 2003. Retrieved 2010-05-31. 
  3. ^ "Raphael C. Lee, MD, ScD, DSc (Hon)". University of Chicago Medical Center. Retrieved 2010-05-31.