Reactive airway disease

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Reactive airway disease
Specialty Pulmonology Edit this on Wikidata

Reactive airway disease is a group of conditions that include reversible airway narrowing due to an external stimulation.[1] These conditions generally result in wheezing.[2]

Conditions within this group include asthma, chronic obstructive pulmonary disease, and viral upper respiratory infections.[1]

The term reactive airway disease may be used in pediatrics to describe an asthma-like syndrome in infants too young for diagnostic testing such as the bronchial challenge test. These infants may later be confirmed to have asthma following testing. The term is sometimes misused as a synonym for asthma.[3]

Reactive airways dysfunction syndrome[edit]

Reactive airways dysfunction syndrome (RADS) is a term proposed by Stuart M. Brooks and colleagues in 1985 [4] to describe an asthma-like syndrome developing after a single exposure to high levels of an irritating vapor, fume, or smoke.[5] It involves coughing, wheezing, and shortness of breath.[6]

It can also manifest in adults with exposure to high levels of chlorine, ammonia, acetic acid or sulphur dioxide, creating symptoms like asthma.[7] These symptoms can vary from mild to fatal, and can even create long-term airway damage depending on the amount of exposure and the concentration of chlorine. Some experts classify RADS as occupational asthma. Those with exposure to highly irritating substances should receive treatment to mitigate harmful effects.[8]

See also[edit]


  1. ^ a b Duke, James (2015). Duke's Anesthesia Secrets. Elsevier Health Sciences. p. 225. ISBN 9780323249782. 
  2. ^ "reactive airway disease" at Dorland's Medical Dictionary
  3. ^ Mayo Clinic Staff (September 4, 2006). "Reactive airway disease: Is it asthma?". Mayo Clinic. Retrieved 2007-04-22. 
  4. ^ S.M. Brooks; M.A. Weiss; I.L. Bernstein. "Reactive airways dysfunction syndrome (RADS): persistent asthma syndrome after high level irritant exposures". Chest, Volume 88, 1985, 376-384. Retrieved 2007-08-28. 
  5. ^ John V. Fahy; Paul M. O'Byrne. ""Reactive airways disease": A lazy term of uncertain meaning that should be abandoned". Am. J. Respir. Crit. Care Med., Volume 163, Number 4, March 2001, 822-823. Retrieved 2007-04-22. 
  6. ^ "reactive airways dysfunction syndrome" at Dorland's Medical Dictionary
  7. ^ Occupational Allergy. Page 1 Drs Rodney Ehrlich and Mohamed F Jeebhay. The Allergy Society of South Africa
  8. ^ Aslan, Sahin; Kandiş, Hayati; Akgun, Metin; Çakır, Zeynep; Inandı, Tacettin; Görgüner, Metin (2006). "The effect of nebulized NaHCO3 treatment on 'RADS' due to chlorine gas inhalation". Inhalation Toxicology. 18 (11): 895–900. doi:10.1080/08958370600822615. 

External links[edit]

External resources