Reedville was named for Simeon Gannett Reed, who was a member of the Oregon Steam Navigation Company, and a prominent figure in Columbia River transportation in 1859-1879. Reed and business partner William S. Ladd operated an 8,000-acre (32 km2) plus hobby farm in the area where they raised livestock and held harness races. His property became the endowment of Reed College after the death of his wife Amanda Reed. Reedville post office was established in 1877 and ran until 1954.
In 2003, Hillsboro opened the Reedville Creek Park, which included the city’s first skate park. By 2004, parts of the community had been annexed into Hillsboro, which led to readdressing of several streets from the county based street numbering to the Hillsboro-based numbering system.