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The term "refractory period" may refer to:
- Refractory period (physiology), the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its resting state following excitation in the areas of biology, physiology, and cardiology
- Refractory period (sex), the recovery phase after orgasm during which it is physiologically impossible for an individual to have additional orgasms
- Psychological refractory period, the delay in response to the second of two closely spaced psychological stimuli
- Postictal state, the period following a series of epileptic seizures during which seizures cannot be induced
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