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Replication may refer to:
- Replication (scientific method), one of the main principles of the scientific method, a.k.a. reproducibility
- Self-replication, the process in which an entity (a cell, virus, program, etc.) makes a copy of itself
- Replication (metallography), the use of thin plastic films to duplicate the microstructure of a component
- Self-replicating machines
- Replication (computing), the use of redundant resources to improve reliability, fault-tolerance, or performance
- Replication (optical media), the manufacture of CDs and DVDs by means other than burning writable discs
- Option replication, a trading strategy to ensure at a certain date the payoff of an option without trading the option
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