The show followed the members of a three-person paramedic team assigned to a fictional Los Angelesfire station, Station 77. Kathleen Ryan returns to work in the pilot episode following an emotional breakdown after a stressful call. Throughout the series, there is obvious romantic tension between Ryan and her partner Michael Bell, who is dating a nurse and struggling with his father, who wants Bell to quit his paramedic job and work for the family company. The third member of the team, Wick Lobo, is a young, energetic rookie eager to prove himself. The main characters shared a high sense of duty and loyalty to each other and their commander, Captain Durfee.