"Resistance" is a song by English alternative rock band Muse, featured on their fifth studio album The Resistance. Written by vocalist, guitarist and pianist Matthew Bellamy, it was released as the third single from the album, following "Uprising" and "Undisclosed Desires", on 22 February 2010. The song makes several references to the novel "1984", by George Orwell. The intro of the song is used in the trailer of the last episode of BBC show Silent Witness. In February 2010, Muse had uploaded a picture puzzle of "Resistance" artwork on their official Facebook page. The puzzle itself has a making of the "Resistance" track (which will be able to see it after solving the puzzle). This song was featured in a promo for an episode of Human Target. The song was also released as downloadable content for the music video game Guitar Hero: Warriors of Rock.
The music video for "Resistance", which features footage of the band performing live on The Resistance Tour, debuted on 14 January 2010, and was directed by Wayne Isham in Madrid (Palacio de los Deportes, 28-November-2009).
On 21 February 2010, "Resistance" entered the UK Rock Chart at #2. Following from its success on the Rock Chart, on 28 February 2010, the single entered the UK Singles Chart as a new entry at #38, beating previous single: "Undisclosed Desires", which only peaked at #49. "Resistance" is now the second Top 40 hit from The Resistance. The same week resulted in "Resistance" climbing to the #1 spot on the UK Rock Chart, as well. On the week of 20 March, it jumped from #6 to #1 on the Billboard Alternative Rock Chart and it became their second number one single on the chart along with their previous single "Uprising".