Response rate (medicine)

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

In medicine, a response rate is the percentage of patients whose cancer shrinks or disappears after treatment. [1]

When used as a clinical endpoint for clinical trials of cancer treatments, this often called the objective response rate (ORR).[2][3]

The FDA definition of ORR is "the proportion of patients with tumor size reduction of a predefined amount and for a minimum time period."[2]:7


  1. ^ "NCI Dictionary of Cancer Terms". National Cancer Institute. Retrieved 5 June 2016.
  2. ^ a b Guidance for Industry Clinical Trial Endpoints for the Approval of Cancer Drugs and Biologics FDA
  3. ^ Objective tumor response and RECIST criteria in cancer clinical trials