A reticular cell is a type of fibroblast that synthesizes collagen alpha-1(III) and uses it to produce reticular fibers. The cell surrounds the fibers with its cytoplasm, isolating it from other tissue components and cells. Reticular cells provide structural support, since they produce and maintain the thin networks of fibres that are a framework for most lymphoid organs.
They are found in many tissues including the spleen, lymph nodes and lymph nodules. They also direct B cells and T cells to specific regions within the tissue.