Rhododendrin

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Rhododendrin
Chemical structure of Rhododendrin
Names
IUPAC name
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[(2R)-4-(4-hydroxyphenyl)butan-2-yl]oxyoxane-3, 4,5-triol
Other names
Betuloside
(-)-Rhododendrin
Identifiers
3D model (Jmol)
ChemSpider
Properties
C16H24O7
Molar mass 328.36 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Rhododendrin (betuloside) is an arylbutanoid glycoside and a phenylpropanoid, a type of natural phenol. It can be found in the leaves of Rhododendron aureum[1] or in Cistus salviifolius.[2]

In vitro, it shows analgesic, anti-inflammatory[1] and diuretic[3] properties.

References[edit]

  1. ^ a b Kim, M. H.; Nugroho, A.; Choi, J.; Park, J. H.; Park, H. J. (2011). "Rhododendrin, an analgesic/anti-inflammatory arylbutanoid glycoside, from the leaves of Rhododendron aureum". Archives of Pharmacal Research. 34 (6): 971–978. doi:10.1007/s12272-011-0614-1. PMID 21725818. 
  2. ^ Danne, A.; Petereit, F.; Nahrstedt, A. (1994). "Flavan-3-ols, prodelphinidins and further polyphenols from Cistus salvifolius". Phytochemistry. 37 (2): 533–538. doi:10.1016/0031-9422(94)85094-1. PMID 7765630. 
  3. ^ Zhang, B; Li, JB; Zhang, DM; Ding, Y; Du, GH (2007). "Analgesic and anti- inflammatory activities of a fraction rich in gaultherin isolated from Gaultheria yunnanensis (Franch.)". Rehder. Biol Pharm Bull. 30 (10): 465–469. doi:10.4103/0973-7847.91102.