Early recorded variations of the name Wheelock have included Quelok, Qwelok, Whelok, Whelocke, with later forms using Wheelock Watter and Wheelock Brooke. The name is said to mean "winding river" and it is reported to have based on the Old Welsh word chwylog, the chwyl part of which means "a turn, a rotation, a course", with an adjective suffix of og. The river has given its name to the large village of Wheelock.
Dodgson, J. McN. (1970a). The place-names of Cheshire. Part one: Country name, regional and forest names, river names, road names, the place-names of Macclesfield hundred. Cambridge: Cambridge University Press. ISBN0-521-07703-6.
Dodgson, J. McN. (1970b). The place-names of Cheshire. Part two: The place-names of Bucklow Hundred and Northwich Hundred. Cambridge: Cambridge University Press. ISBN0-521-07914-4.