Ro-318220

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Ro-318220
Ro-318220.png
Names
IUPAC name
3-(3-(4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl carbamimidothioate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
Properties
C25H23N5O2S
Molar mass 457.55 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Ro-318220 is a protein kinase C (PKC) inhibitor of the bisindolylmaleimide class.[1]

References[edit]

  1. ^ Beltman, Jerlyn; Frank McCormick; Simon J. Cook (1996). "The Selective Protein Kinase C Inhibitor, Ro-31-8220, Inhibits Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression, Induces c-Jun Expression, and Activates Jun N-terminal Kinase". Journal of Biological Chemistry. 271: 27018–27024. doi:10.1074/jbc.271.43.27018.