Ro67-4853 is a drug used in scientific research, which acts as a selective positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR. 1   It was derived by modification of the simpler compound  Ro01-6128, and has itself subsequently been used as a lead compound to develop a range of potent and selective mGluR 1 positive modulators.  
References [ edit ]
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^ Vieira E, Huwyler J, Jolidon S, Knoflach F, Mutel V, Wichmann J (March 2009). "Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers". Bioorganic & Medicinal Chemistry Letters. 19 (6): 1666–9. doi: 10.1016/j.bmcl.2009.01.108. PMID 19233648.