Nacino was born in Baguio City and was raised in Singapore and Laguna, his father's hometown. He studied Nursery up to Primary 6 in Singapore, and also learned to speak Mandarin as his Mother Tongue during his grade school days. He studied in Makati Hope Christian School for his secondary education and in Mapúa Institute of Technology on his tertiary, in which he passed the Nursing Board Exam making him a registered nurse on June 6 and 7, 2009 in Manila.
On his first year of college at Mapua Makati, he participated in the Mister and Miss Cardinals and won as Mister Cardinals 2005. This opened new opportunities in the world of TV commercials and print media. Among his projects were TV commercials and print media for Vaseline, Skyflakes, Goya, Jollibee, Chowking, Smart, Pepsi and STI. His sports are jiujitsu, muay thai, mixed martial arts, boxing, arnis and basketball. He also trains wing chun regularly. Aside from these sports, he also plays drums and a little of guitar.
His biggest break on television was when he bagged the role he had auditioned for – Sine Novela Presents: Gumapang Ka sa Lusak, opposite Jennylyn Mercado and Dennis Trillo. This was followed by another teleserye at GMA Network’s Dramarama sa Hapon block, Koreana, with Kris Bernal as his love interest. His excellent performance in Koreana gave him his first acting nomination from the Entertainment Press Society (Enpres) as Finalist for Outstanding Performance by an Actor for the Golden TV Awards in 2011. With the large viewership and high ratings garnered by Koreana, Nacino was given a more challenging project and an even better exposure via the first-ever dance serye Time of My Life, with Kris Bernal and Mark Herras; which was telecast in GMA’s Telebabad timeslot.