Rolf Apweiler

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Rolf Apweiler
ISMB Fellows 2015.jpg
Rolf Apweiler (third from left) in 2015.
Alma mater
Thesis Characterization of the effect of (-) - 2- (4-methylphenoxy) -7- (4-chlorophenyl) -heptanoic acid on insulin sensitivity and glucose tolerance of FA-FA and FA -? - Rats (1994)
Doctoral students
Known for
Notable awards

Rolf Apweiler is a director of European Bioinformatics Institute (EBI) part of the European Molecular Biology Laboratory (EMBL)[16][17] with Ewan Birney.[18][19]


Apweiler gained his PhD in Biochemistry from Heidelberg University.[20][21]


Apweiler has been working on the Swiss-Prot[22] protein sequence database since 1987, and in 1994 he became leader of the Swiss-Prot group. He has been joint head of the Protein and Nucleotide Data (PANDA) Group since 2007. The PANDA group is involved in several international collaborations like the Human Proteome Organization (HUPO) Proteomics Standards Initiative. Apweiler is a member of the Nomenclature Committee of IUBMB, the FlyBase advisory board, the committee of the Helmholtz Centre for Infection Research (HZI) and the advisory board of the Human Proteome Resource (HPR).

Apweiler is an editor of the FEBS Journal and a section editor of BMC Bioinformatics and has published more than 200 papers.[23][24][25]

Awards and honours[edit]

Apweiler was elected a member of the European Molecular Biology Organization (EMBO) in 2012[14] and made a Fellow of the International Society for Computational Biology in 2015.[15]


  1. ^ "Dr. Rolf Apweiler, European Bioinformatics Institute EMBL-EBI (ELIXIR)". Archived from the original on 2015-07-07. 
  2. ^ Foster, Joseph Michael (2012). Transomics : integrating core 'omics' concepts (PhD thesis). University of Cambridge. 
  3. ^ Foster, Joseph M.; Moreno, Pablo; Fabregat, Antonio; Hermjakob, Henning; Steinbeck, Christoph; Apweiler, Rolf; Wakelam, Michael J. O.; Vizcaíno, Juan Antonio (2013). "LipidHome: a database of theoretical lipids optimized for high throughput mass spectrometry lipidomics". PLOS ONE. Public Library of Science. 8 (5): e61951. doi:10.1371/journal.pone.0061951. PMC 3646891Freely accessible. PMID 23667450.  open access publication – free to read
  4. ^ Ilsey, Garth (2010). A statistical model relating transcription factor concentrations to positional information in the early Drosophila embryo (Ph.D. thesis). University of Cambridge. 
  5. ^ Mueller, Michael (2009). Integrated analysis of proteomics data to assess and improve the scope of mass spectrometry based genome annotation (Ph.D. thesis). University of Cambridge. 
  6. ^ Mueller, M.; Martens, L.; Apweiler, R. (2007). "Annotating the human proteome: Beyond establishing a parts list". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774 (2): 175–191. doi:10.1016/j.bbapap.2006.11.011. PMID 17223395. 
  7. ^ Evgenia, Kriventseva (2004). Computational analysis of complete proteomes by clustering and analysis of alternative splicing impact on proteome diversity (Ph.D. thesis). University of Cambridge. 
  8. ^ Kriventseva, E. V.; Servant, F.; Apweiler, R. (2003). "Improvements to CluSTr: The database of SWISS-PROT+TrEMBL protein clusters". Nucleic Acids Research. 31 (1): 388–389. doi:10.1093/nar/gkg035. PMC 165482Freely accessible. PMID 12520029. 
  9. ^ Möller, Steffen (2001). An environment for consistent sequence annotation and its application to transmembrane proteins (PDF) (Ph.D. thesis). University of Cambridge. Archived from the original (PDF) on 15 February 2010. 
  10. ^ Möller, S.; Croning, M. D.; Apweiler, R. (2001). "Evaluation of methods for the prediction of membrane spanning regions". Bioinformatics (Oxford, England). 17 (7): 646–653. doi:10.1093/bioinformatics/17.7.646. PMID 11448883. 
  11. ^ "Rolf Apweiler -". Retrieved 27 June 2011. 
  12. ^ Bairoch, A.; Apweiler, R.; Wu, C. H.; Barker, W. C.; Boeckmann, B.; Ferro, S.; Gasteiger, E.; Huang, H.; Lopez, R.; Magrane, M.; Martin, M. J.; Natale, D. A.; O'Donovan, C.; Redaschi, N.; Yeh, L. S. (2004). "The Universal Protein Resource (UniProt)". Nucleic Acids Research. 33 (Database issue): D154–D159. doi:10.1093/nar/gki070. PMC 540024Freely accessible. PMID 15608167. 
  13. ^ Hunter, S.; Apweiler, R.; Attwood, T.; Bairoch, A.; Bateman, A.; Binns, D.; Bork, P.; Das, U.; Daugherty, L.; Duquenne, L.; Finn, R. D.; Gough, J.; Haft, D.; Hulo, N.; Kahn, D.; Kelly, E.; Laugraud, A.; Letunic, I.; Lonsdale, D.; Lopez, R.; Madera, M.; Maslen, J.; McAnulla, C.; McDowall, J.; Mistry, J.; Mitchell, A.; Mulder, N.; Natale, D.; Orengo, C.; Quinn, A. F. (Jan 2009). "InterPro: the integrative protein signature database". Nucleic Acids Research. 37 (Database issue): D211–D215. doi:10.1093/nar/gkn785. ISSN 0305-1048. PMC 2686546Freely accessible. PMID 18940856.  open access publication – free to read
  14. ^ a b "The EMBO Pocket Directory" (PDF). European Molecular Biology Organization. Archived from the original on 2015-03-16. 
  15. ^ a b "Meet the ISCB Fellows Class of 2015". Retrieved 20 February 2015. 
  16. ^ Rolf Apweiler page at the EBI
  17. ^ Rolf Apweiler on LinkedIn
  18. ^ Rolf Apweiler publications from Europe PubMed Central
  19. ^ Carninci, P; Kasukawa, T; Katayama, S; Gough, J; Frith, M. C.; Maeda, N; Oyama, R; Ravasi, T; Lenhard, B; Wells, C; Kodzius, R; Shimokawa, K; Bajic, V. B.; Brenner, S. E.; Batalov, S; Forrest, A. R.; Zavolan, M; Davis, M. J.; Wilming, L. G.; Aidinis, V; Allen, J. E.; Ambesi-Impiombato, A; Apweiler, R; Aturaliya, R. N.; Bailey, T. L.; Bansal, M; Baxter, L; Beisel, K. W.; Bersano, T; et al. (2005). "The transcriptional landscape of the mammalian genome". Science. 309 (5740): 1559–63. doi:10.1126/science.1112014. PMID 16141072. 
  20. ^ Apweiler, Rolf (1994). Charakterisierung der Wirkung von ( - )-2-(4-Methylphenoxy)-7-(4-Chlorophenyl)-Heptansäure auf die Insulinsensitivität und Glucosetoleranz von fa-fa- und FA-?-Ratten (PhD thesis). University of Heidelberg. OCLC 75488289. 
  21. ^ Rolf Apweiler page at Archived February 22, 2014, at the Wayback Machine.
  22. ^ Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M. C.; Estreicher, A.; Gasteiger, E.; Martin, M. J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M. (2003). "The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003". Nucleic Acids Research. 31 (1): 365–370. doi:10.1093/nar/gkg095. PMC 165542Freely accessible. PMID 12520024. 
  23. ^ Rolf Apweiler in Google Scholar
  24. ^ Rolf Apweiler at DBLP Bibliography Server
  25. ^ Apweiler, Rolf's publications indexed by the Scopus bibliographic database, a service provided by Elsevier. (subscription required)
Academic offices
Preceded by
Janet Thornton
Director of the European Bioinformatics Institute