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Virus classification
Group: Group V ((-)ssRNA)
Order: Mononegavirales
Family: Paramyxoviridae
Genus: Rubulavirus
Type species
Mumps virus

Rubulavirus is a genus of viruses in the family Paramyxoviridae, order Mononegavirales. Humans, apes, pigs, and dogs serve as natural hosts. There are currently seven species in this genus. Diseases associated with this genus include: mumps.[1][2]


Genus Rubulavirus: species and their viruses[3]
Genus Species Virus (Abbreviation)
Rubulavirus Human parainfluenza virus 2 human parainfluenza virus 2 (HPIV-2)
Human parainfluenza virus 4 human parainfluenza virus 4a (HPIV-4a)
human parainfluenza virus 4b (HPIV-4b)
Mapuera virus Mapuera virus (MapV)
Mumps virus* mumps virus (MuV)
bat mumps virus (BMV)
Parainfluenza virus 5 parainfluenza virus 5 (PIV-5)
Porcine rubulavirus La Piedad Michoacán Mexico virus (LPMV)
Simian virus 41 simian virus 41 (SV-41)

Table legend: "*" denotes type species.

Related Viruses[edit]

Viruses of this genus appear to be most closely related to avulaviruses.[4]


Rubulavirions are enveloped, with spherical geometries. The diameter is around 150 nm. Rubulavirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.[1]

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
Rubulavirus Spherical Enveloped Linear Monopartite

Life Cycle[edit]

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering, through co-transcriptional RNA editing is the method of transcription. The virus exits the host cell by budding. Humans, apes, pigs, and dogs serve as the natural host. Transmission routes are respiratory and saliva.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
Rubulavirus Humans; apes; pigs; dogs None Glycoprotein Budding Cytoplasm Cytoplasm Aerosols; saliva


  1. ^ a b c "Viral Zone". ExPASy. Retrieved 13 August 2015. 
  2. ^ ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015. 
  3. ^ Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (2016-08-01). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. doi:10.1007/s00705-016-2880-1. ISSN 1432-8798. PMC 4947412free to read. PMID 27216929. 
  4. ^ McCarthy AJ, Goodman SJ (2010) Reassessing conflicting evolutionary histories of the Paramyxoviridae and the origins of respiroviruses with Bayesian multigene phylogenies. Infect Genet Evol 10(1):97–107

External links[edit]