|Group:||Group V ((-)ssRNA)|
Rubulavirus is a genus of viruses in the family Paramyxoviridae, order Mononegavirales. Humans, apes, pigs, and dogs serve as natural hosts. There are currently seven species in this genus. Diseases associated with this genus include: mumps.
|Rubulavirus||Human parainfluenza virus 2||human parainfluenza virus 2 (HPIV-2)|
|Human parainfluenza virus 4||human parainfluenza virus 4a (HPIV-4a)|
|human parainfluenza virus 4b (HPIV-4b)|
|Mapuera virus||Mapuera virus (MapV)|
|Mumps virus*||mumps virus (MuV)|
|bat mumps virus (BMV)|
|Parainfluenza virus 5||parainfluenza virus 5 (PIV-5)|
|Porcine rubulavirus||La Piedad Michoacán Mexico virus (LPMV)|
|Simian virus 41||simian virus 41 (SV-41)|
Table legend: "*" denotes type species.
Rubulavirions are enveloped, with spherical geometries. The diameter is around 150 nm. Rubulavirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.
|Genus||Structure||Symmetry||Capsid||Genomic Arrangement||Genomic Segmentation|
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering, through co-transcriptional RNA editing is the method of transcription. The virus exits the host cell by budding. Humans, apes, pigs, and dogs serve as the natural host. Transmission routes are respiratory and saliva.
|Genus||Host Details||Tissue Tropism||Entry Details||Release Details||Replication Site||Assembly Site||Transmission|
|Rubulavirus||Humans; apes; pigs; dogs||None||Glycoprotein||Budding||Cytoplasm||Cytoplasm||Aerosols; saliva|
- "Viral Zone". ExPASy. Retrieved 13 August 2015.
- ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015.
- Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (2016-08-01). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. doi:10.1007/s00705-016-2880-1. ISSN 1432-8798. PMC . PMID 27216929.
- McCarthy AJ, Goodman SJ (2010) Reassessing conflicting evolutionary histories of the Paramyxoviridae and the origins of respiroviruses with Bayesian multigene phylogenies. Infect Genet Evol 10(1):97–107