Russ Altman

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Russ Biagio Altman
Russ Altman.jpg
Russ Altman speaking at ISMB 2014.
Institutions Stanford University
Alma mater Harvard College
Stanford University
Thesis Exclusion Methods for the Determination of Protein Structure from Experimental Data (1989)
Doctoral students Olga Troyanskaya[1]
Known for PharmGKB[2]
Notable awards ISCB Fellow (2010)

Russ Biagio Altman is a scientist at Stanford University Medical School,[3] where he is chair of the department of Bioengineering and director of the program in Biomedical Informatics.[4][5][6] He is a past president and one of the founding members of the International Society for Computational Biology.

External video
What really happens when you mix medications?, 14:41, TED talks[7]

He is also an attending physician in Menlo Park, California, and is the principal investigator for the PharmGKB knowledgebase.[2][8]

In February 2006, Altman gave a presentation at Google, in which he explained the opportunities for pharmacogenomics.[9] In August 2007, Altman was interviewed by Kromosoft, in which he discussed the emerging trends in pharmacogenomics.[10] On November 2, 2007, Altman delivered the IEEE Computer Society's BioInformatics and BioMedicine (BIBM) conference keynote lecture on combining simulation and machine learning to recognize function in 4D.[11] Altman is North American Associate Editor of Briefings in Bioinformatics and an honorary consulting editor for the International Society of Intelligent Biological Medicine, and in 2010 was elected as a fellow for the International Society for Computational Biology.[12] Altman is currently the principal investigator of the Iranian Genome Project, at


Altman received his AB in Biochemistry and Molecular Biology in 1983 from Harvard College,[13] his PhD in Medical Information Sciences from Stanford in 1989 and his MD also from Stanford in 1990.[14]


  1. ^ Mullins, J.; Morrison Mckay, B. (2011). "International Society for Computational Biology Honors Michael Ashburner and Olga Troyanskaya with Top Bioinformatics/Computational Biology Awards for 2011". PLoS Computational Biology. 7 (6): e1002081. doi:10.1371/journal.pcbi.1002081. PMC 3107244free to read. 
  2. ^ a b Altman, R. B. (2007). "PharmGKB: A logical home for knowledge relating genotype to drug response phenotype". Nature Genetics. 39 (4): 426–426. doi:10.1038/ng0407-426. PMC 3203536free to read. PMID 17392795. 
  3. ^ Russ Altman, MD, PhD
  4. ^ Troyanskaya, O.; Cantor, M.; Sherlock, G.; Brown, P.; Hastie, T.; Tibshirani, R.; Botstein, D.; Altman, R. (2001). "Missing value estimation methods for DNA microarrays". Bioinformatics. 17 (6): 520–525. doi:10.1093/bioinformatics/17.6.520. PMID 11395428. 
  5. ^ Garber, M. E.; Troyanskaya, O. G.; Schluens, K.; Petersen, S.; Thaesler, Z.; Pacyna-Gengelbach, M.; Van De Rijn, M.; Rosen, G. D.; Perou, C. M.; Whyte, R. I.; Altman, R. B.; Brown, P. O.; Botstein, D.; Petersen, I. (2001). "Diversity of gene expression in adenocarcinoma of the lung". Proceedings of the National Academy of Sciences. 98 (24): 13784–13789. Bibcode:2001PNAS...9813784G. doi:10.1073/pnas.241500798. 
  6. ^ Raychaudhuri, S.; Stuart, J.; Altman, R. (2000). "Principal components analysis to summarize microarray experiments: Application to sporulation time series". Pacific Symposium on Biocomputing: 455–466. PMC 2669932free to read. PMID 10902193. 
  7. ^ "What really happens when you mix medications?". TED (talks). Retrieved April 2, 2016. 
  8. ^ "PharmGKB: The Pharmacogenetics and Pharmacogenomics Knowledge Base". Archived from the original on 2006-04-19. Retrieved 2007-09-06. 
  9. ^ "Opportunities For Pharmacogenomics and Personalized Medicine". Retrieved 2007-09-06. 
  10. ^ "Current and Emerging Trends in Pharmacogenomics". Retrieved 2007-09-06. 
  11. ^ Halperin, I.; Glazer, D. S.; Wu, S.; Altman, R. B. (2008). "The FEATURE framework for protein function annotation: Modeling new functions, improving performance, and extending to novel applications". BMC Genomics. 9: S2. doi:10.1186/1471-2164-9-S2-S2. 
  12. ^
  13. ^ Altman, R.; Ladner, J.; Lipscomb, W. (1982). "Quaternary structural changes in aspartate carbamoyltransferase of Escherichia coli at pH 8.3 and pH 5.8". Biochemical and Biophysical Research Communications. 108 (2): 592–595. doi:10.1016/0006-291X(82)90869-5. PMID 6756403. 
  14. ^ Russ Altman, Community Academic Profile
Preceded by
Lawrence Hunter
President of the
International Society for Computational Biology

2000 – 2002
Succeeded by
Philip Bourne