Russell bodies

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Plasmacytoma with abundant Russell bodies. H&E stain.

Russell bodies are eosinophilic, large, homogenous immunoglobulin-containing inclusions usually found in a plasma cell undergoing excessive synthesis of immunoglobulin; the Russell body is characteristic of the distended endoplasmic reticulum.

This is one cell variation found in multiple myeloma.[1]

They are named for William Russell (1852-1940), a Scottish Physician.[2][3]

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  1. ^ Martín-Noya A, Ríos-Herranz E, Rafel-Ribas E (February 1999). "Multiple myeloma with numerous intranuclear Russell bodies". Haematologica 84 (2): 179–80. PMID 10091418. 
  2. ^ synd/1962 at Who Named It?
  3. ^ Russell, W (13 December 1890). "An Address on a Characteristic Organism of Cancer". British Medical Journal (BMJ) 2 (1563): 1356–1360. doi:10.1136/bmj.2.1563.1356. PMC 2208600. PMID 20753194. 

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